A recent scientific success of EKOL

Shortly after the appearance on the homepage of National Geographic Hungary, once again an important EKOL research achieved a significant scientific success. The study published in the Food Additives and Contaminants makes migration studies for certain additive–food simulant pairs dispensable.

Solubility values for six UV stabilisers and five antioxidants were determined by Zsolt Bodai and his colleagues in all the liquid food simulants proposed in European Union Regulation No. 10/2011/EC, as well as in fruit juice and cola drink. The applied method was obtained by modification of the method for the determination of water solubility as described in OECD guideline Test No. 105.

By using ultrasonication and shorter equilibration time, the time demand of the solubility determinations was decreased notably. Solubility values proved to be lower than the specific migration limits (as specified in 10/2011/EC) at 25°C for almost all target compounds in food simulants A, B, C and D1 as well as in fruit juice and cola drink. The exceptions were Tinuvin P and Irganox 3790 in simulant D1.

The solubility in food simulant D2 was higher than 1000 μg/ml for all target compounds. These results show that the solubility of some additives in food simulants can be so low that it makes migration studies for certain additive–food simulant pairs dispensable.

The writer and the co-writers of the study: Zsolt Bodai, Péter Pál Jakab, Márton Novák, Zoltán Nyiri, Bálint Sámuel Szabó, Tamás Rikker and Zsuzsanna Eke.  

The publication is a big success of the Separation Science Research and Education Laboratory (EKOL), established by the Faculty of Science and the Institute of Chemistry of Eötvös Loránd University, together with WESSLING Hungary Kft.