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Method overview
Our state-of-the-art equipment and knowledge of our experts at both locations in Münster and Budapest characterise the pharmaceutical analysis of the WESSLING Group.
Methods in pharmaceutical analysis at WESSLING
Our comprehensive instrumental equipment enables us to provide our customers with a full service from a single source. Our international and interdisciplinary cooperation between Münster and Budapest enables us to offer our analyses both quickly and flexibly. At WESSLING, proven experts with their expertise are at your disposal for integrated solutions. They offer a wide range of methods of pharmaceutical technology.
General methods
- Laser diffractometry, EP 2.9.31: determination of particle size
- IR-microscopy (transmission / reflection / ATR): testing for drug authenticity / drug counterfeits, analysis of film thickness
- Characterisation of nanomaterials in ready-to-use medicinal products
- Spectroscopy / spectrometry: IR spectroscopy, UV-VIs spectroscopy, mass spectrometry, mass spectrometry with inductively coupled plasma (ICP-MS/OES)
- Thin layer chromatography: identity testing, semiquantitative purity tests, quantitative purity tests, content determinations
- Gas chromatography (GC, GC-MS): content determination / determination of RLM, identity checks, detectors: DAD, MS, TCD, feed systems: head space and split / splitless
- Liquid chromatography (HPLC, HPLC-MS): content determination, testing for related substances, identity checks, detectors: fluorescence, DAD, UV/Vis, MS, RI
- Sterility tests using two isolators
- Endotoxin determinations, method A and C
- Test for absence of THC
- Paper chromatography
- Determination of total organic carbon (TOC)
- Clarity and opalescence of liquids
- Colouring of liquids
- Conductivity
- pH value: potentiometric method, indicator method
- Relative density
- Drying loss
- Potentiometric titration
- Optical rotation
- Viscosity (rotational viscometry)
- Brookfield viscosity
- Refractive index
- Melting temperature
- Boiling temperature
- Distillation area
Identity testing of pharmaceuticals
- Ions and functional groups
- Fatty oils by thin-layer chromatography
- Phenothiazines by thin layer chromatography
Limit tests for pharmaceuticals
- Ammonium
- Arsenic
- Calcium
- Chloride
- Magnesium
- Heavy metals
- Iron
- Phosphate
- Potassium
- Sulfate
- Ash/sulphated ash
- Free formaldehyde
- Alkaline reacting substances in fatty oils
- Determination of metal residues
- Testing of fatty oils for foreign oils by thin layer chromatography
- Fatty acid composition
- Sterols in fatty oils
- Determination of solvent residues
Determination of the content of pharmaceuticals
- Acid value
- Ester value
- Hydroxyl number
- Iodine number
- Peroxide number
- Saponification number
- unsaponifiable parts
- Complexometric titration
- Karl Fischer method
- Phenol in sera and vaccines
- Protein in polysaccharide vaccines
- Nucleic acids in polysaccharide vaccines
- Phosphorus in polysaccharide vaccines
- Protein content
Methods of pharmacognosy
- Ash insoluble in hydrochloric acid
- Foreign components
- Stomata Index
- Source number
- Pesticides
- Determination of tannin content in herbal drugs
- Bitter value
- Dry residue and drying loss of extracts
- Aflatoxins B1 in herbal drugs
- Analysis for aistolochic acids in herbal drugs
- Ochratoxin in herbal drugs
- Microscopic examination of herbal drugs
Methods of pharmaceutical technology
- Laser diffractometry, EP 2.9.31: determination of particle size
- IR-microscopy (transmission / reflection / ATR): testing for drug authenticity / drug counterfeits, analysis of film thickness)
- Characterisation of nanomaterials in ready-to-use medicinal products
- Spectroscopy / spectrometry: IR spectroscopy, UV-VIs spectroscopy, mass spectrometry, mass spectrometry with inductively coupled plasma (ICP-MS/OES)
- Thin layer chromatography: identity testing, semiquantitative purity tests, quantitative purity tests, content determinations
- Gas chromatography (GC, GC-MS): content determination / determination of RLM, identity checks, detectors: FID, MS, TCD, feed systems: head space and split / splitless
- Liquid chromatography (HPLC, HPLC-MS): content determination, testing for related substances, identity checks, detectors: fluorescence, DAD, UV/Vis, MS, RI
- Sterility tests using two isolators
- Endotoxin determinations, method A and C
- Test for absence of THC
- Determination of total organic carbon (TOC)
- Clarity and opalescence of liquids
- Colouring of liquids
- Conductivity
- pH value: potentiometric method, indicator method
- Relative density
- Loss Drying
- Potentiometric titration
- Optical rotation
- Brookfield viscosity
- Refractive index
- Melting temperature
- Boiling temperature
- Distillation area
Identity testing of pharmaceuticals
- Ions and functional groups
- Fatty oils by thin-layer chromatography
- Phenothiazines by thin layer chromatography